Dasari, R.; Blauz, A.; Medellin, D.; Kassim, R.; Viera, C.; Santarosa, M.; Van der Westhuyzen, A.; van Otterlo, W.; Olivas, T.; Yildiz, T.; Betancourt, T.; Shuster, C.B.; Rogelj, S.; Rychlik, B.; Hudnall, T.; Frolova, L.; Kornienko, A. Chem. Med. Chem., 2018, Article ASAP. Link

Wang, K.W.; Betancourt, T.; Hall, C. K. Computational study of DNA-cross-linked hydrogel formation for drug delivery applications. Macromolecules. 2018, 51, 9758-9768. Link


Yildiz, T.; Gu, R.; Zauscher, S.; Betancourt, T. Doxorubicin-loaded protease-activated near-infrared fluorescent polymeric nanoparticles for imaging and therapy of cancer. Int. J. Nanomed. 2018, 13, 6961-6986. Link

Wang, K.W.; Barker, K.; Benner, S.; Betancourt, T.; Hall, C. Development of a simple coarse-grained model for analysis of oligonucleoutide complex formation. Molecular Simulations. 2018, 4, 1004-1015. Link



Rodriguez Amaya, L.; Betancourt, T.; Henry Collins, K.; Hinojosa, O.; Corona, C. Undergraduate research experiences: mentoring, awareness, and perceptions – a case study at a Hispanic-serving institution. Int. J. STEM. Ed. 2018, 5, 9. Link

Rastogi, S.K.; Anderson, H.E.; Lamas, J.; Barret, S.; Cantu, T.; Zauscher, S.; Brittain, W.J.; Betancourt, T. Enhanced Release of Molecules upon UV Light Irradiation from Photoresponsive Hydrogels Prepared from Bifunctional Azobenzene and Four-Arm Poly(ethylene glycol). ACS Applied Materials & Interfaces. 2018, 10, 30071-30080. Link

Graphical Abstract

Jamkhindikar, S. P.; Stretz, H. A.; Massingill, J. Jr.; Betancourt, T.; High throughput fiber reactor process for organic nanoparticle production: Poly(N-isopropylacrylamide), poly(acrylamide), and alginate. J. Applied Polym. Sci. 2017, 134, 45524. Link 

Ciavatta, M. L.; Lefranc, F.; Carbone, M.; Mollo, E.; Gavagnin, M.; Betancourt, T.; Dasari, R.; Kornienko, A.*; Kiss, R.* Anticancer Compounds from Marine Mollusks. Medicinal Research Reviews. 2017, 37 (4), 702-801. Link

Cantu T.; Walsh, K.; Pattani, V.; Moy, A.; Tunnell, J.; Irvin, J.; Betancourt, T.; Conductive Polymer-Based Nanoparticle for Laser-Mediated Photothermal Ablation of Cancer: Synthesis, Characterization, and In Vitro Evaluation. International Journal of Nanomedicine. 2017, 17, 615-632. Link

Weigum, S.; Munoz, C.; McIvor, E.; Sutton, M.; Feng, R.; Cantu, T.; Betancourt, T. Targeted Therapy of Hepatocellular Carcinoma with Aptamer-Functionalized Biodegradable Nanoparticles. Journal of Nanoparticle Research. 2016, 18, 341. Link

Hamon, C.; Dorsey, C.; Ozel, T.; Barnes, E. ; Hudnall, T.; Betancourt, T.; Near Infrared Aza-BODIPY Dye Loaded Biodegradable Polymeric Nanoparticles for Optical Cancer Imaging. Journal of Nanoparticle Research. 2016, 18, 207. Link

Cantu T.; Rodier, B.; Iszard, Z.; Kilian, A.; Pattani, V.; Walsh, K.; Weber, K.; Tunnell, J.; Betancourt, T.;Irvin, J. Electroactive Polymer Nanoparticles Exhibiting Photothermal Properties. Journal of Visualized Experiments. 2016, Issue 107, e5363. Link

Medellin, Derek; Zhou, Qiong; Scott, Robert; Hill, R.; Frail, R.; Dasari, Ramesh; Ontiveros, Steven; Pelly, Stephen; van Otterlo, Willem; Betancourt, Tania; Shuster, Charles; Hamel, Ernest; Bai, Ruoli; LaBarbera, Daniel; Rogelj, Snezna; Frolova, Liliya; Kornienko, Alexander*. Novel Microtubule-Targeting 7-Deazahypoxanthines Derived from Marine Alkaloid Rigidins with Potent In Vitro and In Vivo Anticancer Activities. Journal of Medicinal Chemistry. 2016, 59, 480-485. Link

Fahami, A.; Beall, G. W.; Betancourt, T. Synthesis, bioactivity and zeta potential investigations of chlorine and fluorine substituted hydroxyapatite. Materials Science and Engineering C. 2016, 59, 78-85. Link

Barker, K.; Rastogi, S. K.; Dominguez, J.; Cantu, T.; Brittain, W.; Irvin, J.; Betancourt, T. Biodegradable DNA-enabled poly(ethylene glycol) hydrogels prepared by copper-free click chemistry. Journal of Biomaterials Science, Polymer Edition. 2015, 27, 22-39. Link

ssDNA H-gelsOzel, T.; White, S.; Nguyen, E.; Moy, A.; Brenes, N.; Choi, B.; Betancourt, T. Enzymatically Activated Near Infrared Nanoprobes Based on Amphiphilic Block Copolymers for Optical Detection of Cancer. Lasers in Medicine and Surgery. 2015, 47, 579-594. Journal Issue CoverLink

Gonzalez; C.M.; Martin, B. and Betancourt T. “Photochemical synthesis of bimetallic and anisotropic Au-containing nanoparticles using a one-step protocol.” J. Mater. Chem. A. 2014, 2, 17574. Link

Frolova, L.V.; Magedov, I.V.; Romero, A.E.; Karki, M.; Otero, I.; Hayden, K.; Evdokimov, N.M.; Banuls, L.M.; Rastogi, S.K.; Smith, W.R.; Lu, S.L.; Kiss, R.; Shuster, C.B.; Hamel, E.; Betancourt, T.; Rogelj, S.; Kornienko, A., Exploring natural product chemistry and biology with multicomponent reactions. 5. Discovery of a novel tubulin-targeting scaffold derived from the rigidin family of marine alkaloids. J. Med. Chem. 2013, 56 (17), 6886-6900. PMDI 23927793. Link

Betancourt T, Pardo J, and Peppas NA. “Characterization of pH-responsive hydrogels of poly(itaconic acid-g-ethylene glycol) prepared by UV-initiated free radical polymerization as biomaterials for oral delivery of bioactive agents.” J. Biomed. Mater. Res. A. 2010, 93(1),175-188. PMID: 19536838. Link

Betancourt T, Byrne J, Sunaryo N., Crowder S, Kadapakkam M, Patel S, Casciato S., and Brannon-Peppas L. “PEGylation strategies for active targeting of PLA/PLGA nanoparticles.” J. Biomed. Mater. Res. A 2009, 91(1), 263-276. Link

Betancourt T, Shah K, and Brannon-Peppas L. “Rhodamine-loaded poly(lactic-co-glycolic acid) nanoparticles for investigation of in vitro interactions with breast cancer cells.” J. Mater. Sci. Mater. Med. 2009, 20(1), 387-395. Link

Byrne J, Betancourt T, Brannon-Peppas L. “Active targeting schemes for nanoparticle systems in cancer therapeutics.” Adv Drug Deliv Rev. 2008, 60(15), 1569-1676. Link

Betancourt T, Brown B, Brannon-Peppas L. “Doxorubicin-loaded PLGA nanoparticles by nanoprecipitation: preparation, characterization and in vitro evaluation.” Nanomedicine. 2007, 2(2), 219-232. Link

Betancourt T, Brannon-Peppas L. “Micro- and nanofabrication methods in nanotechnological medical and pharmaceutical devices.” Int. J. Nanomed. 2006, 1(4), 484-495. Link