Bretin, L.; Husiev, Y.; Ramu, V.; Zhang, L.; Hakkennes, M.; Abyar, S.; Johns, A. C.; Le Dévédec, S. E.; Betancourt, T.; Kornienko, A.; Bonnet, S. Red-Light Activation of Microtubule Polymerization Inhibitor via Amide Functionalization of the Ruthenium Photocage. Angewandte Chemie. 2023, e202316425. DOI 10.1002/anie.202316425.

Thapa, K.; FitzSimons, T. M.; Otakpor, M. U.; Siller, M. M.; Crowell, A. D.; Zepeda, J. E.; Torres, E.; Roe, L. N.; Arts, J.; Rosales, A.; Betancourt, T. Photothermal Modulation of Dynamic Covalent Poly(ethylene glycol)/PEDOT Composite Hydrogels for On-Demand Drug Delivery. ACS Applied Materials & Interfaces. 2023, 15, 52180-52196.. DOI 10.1021/acsami.3c11288.

Haya, G.; Runsewe, D. O.; Otakpor, M. U.; Pohlman, G. E.; Towne, A.; Betancourt, T.; Irvin, J. A. Functionalized Thiophene-Based Aptasensors for the Electrochemical Detection of Mucin-1. ACS Applied Polymer Materials 2023, 5, 1208-1218. Link

Heshmati Aghda, N.; Dabbaghianamiria, M.; Tunnell, J. W.; Betancourt, T. Design of Smart Nanomedicines for Effective Cancer Treatment. Int. J. Pharm. 2022, 621, 121791. Link

Runsewe, D. O.; Haya, G.; Irvin, J. A.; Betancourt, T. Conducting Polymer-Based Electrochemical Aptasensor for the Detection of Adenosine. ACS Applied Polymer Materials 2021, 3, 6674-6683. Link

Heshmati Aghda, N.; Torres Hurtado, S.; Abdulsahib, S. M.; Lara, E. J.; Tunnell, J.; Betancourt, T. Dual Photothermal/Chemotherapy of Melanoma Cells with Albumin Nanoparticles Carrying Indocyanine Green and Doxorubicin Leads to Immunogenic Cell Death. Macromol. Biosci. 2021, 2100353, Link

Aksenov, A.V.; Arutiunov, N.A.; Kirilov, N. K.; Adsenov, D. A.; Grishin, I. Y.; Aksenov, N. A.; Wang, H.; Du, L.; Betancourt, T.; Pelly, S. C.; Kornienko, A.; Rubin, M. [3+2]-Annulation of pyridinium ylides with 1-chloro-2-nitrostyrenes unveils a tubulin polymerization inhibitor. Org. Biomol. Chem., 2021, 19, 7234-7245. Link

Nguyen, H. T. M.; Katta, N.; Widman, J. A.; Takematsu, E.; Feng, X.; Torres-Hurtado, S. A.; Betancourt, T.; Baker, A. B.; Suggs, L. J.; Milner, T. E.; Tunnells, J. W. Laser Nanobubbles Induce Immunogenic Cell Death in Breast Cancer. Nanoscale, 2021, 13, 3644-3653. Link

Rastogi, S. K.; Zhao, Z.; Gildner, M. B.; Shoulders, B.; Velasquez, T. L.; Blumenthal, M. O.; Wang, L.; Li, X.; Hudnall, T. W.; Betancourt, T.; Du, L.; Brittain, W. J. Synthesis, Optical Properties and in vitro Cell Viability of Novel Spiropyrans and their Photostationary States. Tetrahedron 2021, 80, 131854. Link

Huff, M. E.; Gokmen, F. O.; Barrera, J. S.; Lara, E. J.; Tunnell, J.; Irvin, J.; Betancourt, T. Induction of Immunogenic Cell Death in Breast Cancer by Conductive Polymer Nanoparticle-Mediated Photothermal Therapy. ACS Appl. Polym. Mater. 2020, 2, 5602-5620. Link

Heshmati Aghda, H.; Abdulsahib, S. M.; Severson, C.; Lara, E. J.; Torres Hurtado, S.; Yildiz, T.; Castillo, J. A.; Tunnell, J. W.; Betancourt, T. Induction of Immunogenic Cell Death of Cancer Cells Through Nanoparticle-Mediated Dual Chemotherapy and Photothermal Therapy. Int. J. Pharm. 2020, 589, 119787. Link

Heshmati Aghda, H.; Lara, E. J.; Patel, P.; Betancourt, T. High Throughput Preparation of Poly(Lactic-Co-Glycolic Acid) Nanoparticles Using Fiber Fluidic Reactor. Materials, 2020, 13(14), 3075. Link

van Rixel, Vi. H. S.; Ramu, V.; Auyeung, A. B.; Beztsinna, N.; Leger, D. Y.; Lameijer, L. N.; Hilt, S. T.; Le Dévédec, S. E.; Yildiz, T.; Betancourt, T.; Gildner, M. B.; Hudnall, T. W.; Sol, V.; Liagre, B.; Kornienko, A.; Bonnet, S. Photo-Uncaging of a Microtubule-Targeting Rigidin Analogue in Hypoxic Cancer Cells and in a Xenograft Mouse Model. J. Am. Chem. Soc., 2019, 141, 18444-18454. Link

Runsewe, D.; Betancourt, T.; Irvin, J.A. Biomedical applications of electroactive polymers in electrochemical sensors: a review. Materials, 2019, 12, 2629. Link

Dasari, R.; Blauz, A.; Medellin, D.; Kassim, R.; Viera, C.; Santarosa, M.; Van der Westhuyzen, A.; van Otterlo, W.; Olivas, T.; Yildiz, T.; Betancourt, T.; Shuster, C.B.; Rogelj, S.; Rychlik, B.; Hudnall, T.; Frolova, L.; Kornienko, A. Microtubule-targeting 7-deazahypoxanthines derived from marine alkaloid rigidins: exploration of the N3 and N9 positions and interaction with multidrug-resistance proteins. Chem. Med. Chem., 2018, 14, 322-333. Link

Wang, K.W.; Betancourt, T.; Hall, C. K. Computational study of DNA-cross-linked hydrogel formation for drug delivery applications. Macromolecules. 2018, 51, 9758-9768. Link

Yildiz, T.; Gu, R.; Zauscher, S.; Betancourt, T. Doxorubicin-loaded protease-activated near-infrared fluorescent polymeric nanoparticles for imaging and therapy of cancer. Int. J. Nanomed. 2018, 13, 6961-6986. Link

Wang, K.W.; Barker, K.; Benner, S.; Betancourt, T.; Hall, C. Development of a simple coarse-grained model for analysis of oligonucleoutide complex formation. Molecular Simulations. 2018, 4, 1004-1015. Link

Rodriguez Amaya, L.; Betancourt, T.; Henry Collins, K.; Hinojosa, O.; Corona, C. Undergraduate research experiences: mentoring, awareness, and perceptions – a case study at a Hispanic-serving institution. Int. J. STEM. Ed. 2018, 5, 9. Link

Rastogi, S.K.; Anderson, H.E.; Lamas, J.; Barret, S.; Cantu, T.; Zauscher, S.; Brittain, W.J.; Betancourt, T. Enhanced Release of Molecules upon UV Light Irradiation from Photoresponsive Hydrogels Prepared from Bifunctional Azobenzene and Four-Arm Poly(ethylene glycol). ACS Applied Materials & Interfaces. 2018, 10, 30071-30080. Link

Jamkhindikar, S. P.; Stretz, H. A.; Massingill, J. Jr.; Betancourt, T.; High throughput fiber reactor process for organic nanoparticle production: Poly(N-isopropylacrylamide), poly(acrylamide), and alginate. J. Applied Polym. Sci. 2017, 134, 45524. Link 

Ciavatta, M. L.; Lefranc, F.; Carbone, M.; Mollo, E.; Gavagnin, M.; Betancourt, T.; Dasari, R.; Kornienko, A.*; Kiss, R.* Anticancer Compounds from Marine Mollusks. Medicinal Research Reviews. 2017, 37 (4), 702-801. Link

Cantu T.; Walsh, K.; Pattani, V.; Moy, A.; Tunnell, J.; Irvin, J.; Betancourt, T.; Conductive Polymer-Based Nanoparticle for Laser-Mediated Photothermal Ablation of Cancer: Synthesis, Characterization, and In Vitro Evaluation. International Journal of Nanomedicine. 2017, 17, 615-632. Link

Weigum, S.; Munoz, C.; McIvor, E.; Sutton, M.; Feng, R.; Cantu, T.; Betancourt, T. Targeted Therapy of Hepatocellular Carcinoma with Aptamer-Functionalized Biodegradable Nanoparticles. Journal of Nanoparticle Research. 2016, 18, 341. Link

Hamon, C.; Dorsey, C.; Ozel, T.; Barnes, E. ; Hudnall, T.; Betancourt, T.; Near Infrared Aza-BODIPY Dye Loaded Biodegradable Polymeric Nanoparticles for Optical Cancer Imaging. Journal of Nanoparticle Research. 2016, 18, 207. Link

Cantu T.; Rodier, B.; Iszard, Z.; Kilian, A.; Pattani, V.; Walsh, K.; Weber, K.; Tunnell, J.; Betancourt, T.;Irvin, J. Electroactive Polymer Nanoparticles Exhibiting Photothermal Properties. Journal of Visualized Experiments. 2016, Issue 107, e5363. Link

Medellin, Derek; Zhou, Qiong; Scott, Robert; Hill, R.; Frail, R.; Dasari, Ramesh; Ontiveros, Steven; Pelly, Stephen; van Otterlo, Willem; Betancourt, Tania; Shuster, Charles; Hamel, Ernest; Bai, Ruoli; LaBarbera, Daniel; Rogelj, Snezna; Frolova, Liliya; Kornienko, Alexander*. Novel Microtubule-Targeting 7-Deazahypoxanthines Derived from Marine Alkaloid Rigidins with Potent In Vitro and In Vivo Anticancer Activities. Journal of Medicinal Chemistry. 2016, 59, 480-485. Link

Fahami, A.; Beall, G. W.; Betancourt, T. Synthesis, bioactivity and zeta potential investigations of chlorine and fluorine substituted hydroxyapatite. Materials Science and Engineering C. 2016, 59, 78-85. Link

Barker, K.; Rastogi, S. K.; Dominguez, J.; Cantu, T.; Brittain, W.; Irvin, J.; Betancourt, T. Biodegradable DNA-enabled poly(ethylene glycol) hydrogels prepared by copper-free click chemistry. Journal of Biomaterials Science, Polymer Edition. 2015, 27, 22-39. Link

Ozel, T.; White, S.; Nguyen, E.; Moy, A.; Brenes, N.; Choi, B.; Betancourt, T. Enzymatically Activated Near Infrared Nanoprobes Based on Amphiphilic Block Copolymers for Optical Detection of Cancer. Lasers in Medicine and Surgery. 2015, 47, 579-594. Journal Issue Cover. Link

Gonzalez; C.M.; Martin, B. and Betancourt T. “Photochemical synthesis of bimetallic and anisotropic Au-containing nanoparticles using a one-step protocol.” J. Mater. Chem. A. 2014, 2, 17574. Link

Frolova, L.V.; Magedov, I.V.; Romero, A.E.; Karki, M.; Otero, I.; Hayden, K.; Evdokimov, N.M.; Banuls, L.M.; Rastogi, S.K.; Smith, W.R.; Lu, S.L.; Kiss, R.; Shuster, C.B.; Hamel, E.; Betancourt, T.; Rogelj, S.; Kornienko, A., Exploring natural product chemistry and biology with multicomponent reactions. 5. Discovery of a novel tubulin-targeting scaffold derived from the rigidin family of marine alkaloids. J. Med. Chem. 2013, 56 (17), 6886-6900. PMDI 23927793. Link

Betancourt T, Pardo J, and Peppas NA. “Characterization of pH-responsive hydrogels of poly(itaconic acid-g-ethylene glycol) prepared by UV-initiated free radical polymerization as biomaterials for oral delivery of bioactive agents.” J. Biomed. Mater. Res. A. 2010, 93(1),175-188. PMID: 19536838. Link

Betancourt T, Byrne J, Sunaryo N., Crowder S, Kadapakkam M, Patel S, Casciato S., and Brannon-Peppas L. “PEGylation strategies for active targeting of PLA/PLGA nanoparticles.” J. Biomed. Mater. Res. A 2009, 91(1), 263-276. Link

Betancourt T, Shah K, and Brannon-Peppas L. “Rhodamine-loaded poly(lactic-co-glycolic acid) nanoparticles for investigation of in vitro interactions with breast cancer cells.” J. Mater. Sci. Mater. Med. 2009, 20(1), 387-395. Link

Byrne J, Betancourt T, Brannon-Peppas L. “Active targeting schemes for nanoparticle systems in cancer therapeutics.” Adv Drug Deliv Rev. 2008, 60(15), 1569-1676. Link

Betancourt T, Brown B, Brannon-Peppas L. “Doxorubicin-loaded PLGA nanoparticles by nanoprecipitation: preparation, characterization and in vitro evaluation.” Nanomedicine. 2007, 2(2), 219-232. Link

Betancourt T, Brannon-Peppas L. “Micro- and nanofabrication methods in nanotechnological medical and pharmaceutical devices.” Int. J. Nanomed. 2006, 1(4), 484-495. Link